Top latest Five ceesdekker.net Urban news
Top latest Five ceesdekker.net Urban news
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Nanotechnology delivers An array of options to lead to biology. In this article I'll existing examples where nanofabrication – the chance to make confined buildings with Proportions at will – is utilized to examine the biophysics of solitary molecules and cells. I will current some illustrations from our lab:
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and close to-infrared fluorescent proteins
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart layout in 2005. (nl)
SMC complexes can move physical roadblocks larger than their ring sizing, indicating a nontopological system for DNA loop extrusion
We use nanofabricated microfluidic structures to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental position of spatial confinement with the molecular and cellular degree. Our tasks consist of the following:
2011, 1st in vitro measurements of transport across an individual biomimetic nuclear pore sophisticated; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the mechanism of homology recognition in DNA homologous recombination
In 1993, like a youthful and keen associate professor at Delft University of Know-how, I'd at first centered the investigate efforts of my group on measuring the electrical conductance of one conducting-polymer molecule. In just two many years, we had made a tool wherein a single wire of a phthalocyaninepolysiloxane polymer was linked amongst two intently spaced metallic nanoelectrodes.
But carbon nanotubes have remained a investigate subject matter of sizeable desire to quite a few. In fact, the outlook on working with carbon nanotubes to develop realistic products, in regions including radio-frequency electronics, digital electronics and flexible electronics, continues to be shiny.
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Cees Dekker is Distinguished College Professor at TU Delft. Qualified for a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes from the nineteen nineties. Due to the fact 2000, he moved to solitary-molecule biophysics and nanobiology. His present study focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, especially SMC motor protein; and (iii) developing a residing synthetic cell from lifeless molecules. Dekker is definitely an elected member of the KNAW and fellow towards the APS and also the IOP.
Visualization of unstained DNA https://www.ceesdekker.net nanostructures with Highly developed in-focus transmission electron microscopy methods
It had been a very intriguing time, through which I received a great deal of aid from Delft University of Know-how, exactly where I used to be a professor at enough time, And that i started a number of collaborations with molecular biologists. That aided me master a great deal.’